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The role of imaging in defining cardiovascular risk to help cancer patient management: a scoping review

  • 0Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena, Italy. dott.roberto.fari@gmail.com.
Insights Into Imaging +

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February 17, 2025

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February 17, 2025

View abstract on PubMed

Summary

This summary is machine-generated.

Routine chest CT scans can identify coronary calcium, a key indicator of cardiovascular risk in cancer patients. This assessment aids in managing treatment side effects and improving patient outcomes.

Area Of Science

  • Cardiology
  • Oncology
  • Radiology

Background

  • Cancer therapies can increase cardiovascular risk, necessitating proactive management.
  • Cardiovascular disease is a significant concern for cancer survivors.

Purpose Of The Study

  • To explore the utility of non-gated chest CT scans in assessing cardiovascular risk in cancer patients.
  • To evaluate the correlation between coronary calcium on non-gated CT and established cardiac CT measures.
  • To determine the association between coronary calcification and cardiovascular events or endothelial damage in cancer patients.

Main Methods

  • A scoping review of PubMed literature was conducted.
  • Searches were designed based on three distinct steps.
  • Included original articles and systematic reviews.

Main Results

  • Non-gated chest CT scans strongly correlate with Agatston scores from cardiac CT (r=0.94).
  • Various scoring methods (Agatston, ordinal, extent, length) are adaptable to non-gated CT.
  • Coronary calcification on non-gated CT predicts cardiovascular risk, including major adverse cardiovascular events and mortality in cancer patients.

Conclusions

  • Radiological assessment of coronary calcium on non-gated CT scans can enhance cardiovascular risk prediction.
  • Standardized practices for CV risk assessment using routine CTs can improve comprehensive cancer care.
  • Non-gated CTs can detect endothelial damage, informing cardiovascular risk management in oncology.

Keywords:

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