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PDE4B promotes JNK/NLRP3 activation in the nucleus pulposus and mediates intervertebral disc degeneration

Weixing Xu1, Rana Dhar2,3, Kaiyue Li2

  • 1Department of Orthopedics, Tongde Hospital of Zhejiang Province, Hangzhou, 310012, Zhejiang, China.

Scientific Reports
|February 17, 2025
PubMed

Keywords:
Intervertebral disc degeneration diseaseNLRP3Nucleus pulposusPhosphodiesterase 4B

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