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Updated: May 27, 2025
05:38
Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
Published on: May 16, 2025
24
An uncommon presentation of discoid lupus suggesting systemic evolution
Ariana Nateghi1, Julie Desrochers2
1Department of Dermatology, Sherbrooke University, Sherbrooke, Canada.
SAGE Open Medical Case Reports
|February 18, 2025
Summary
Discoid lupus erythematosus (DLE) can present unusually, affecting palms, soles, and the perineum. Recognizing these rare symptoms is crucial for managing potential systemic disease progression.
Area of Science:
- Dermatology
- Rheumatology
- Autoimmune Diseases
Background:
- Discoid lupus erythematosus (DLE) is a chronic autoimmune skin condition.
- DLE typically affects the head and neck.
- Palmoplantar involvement (ppDLE) is an uncommon DLE presentation.
Observation:
- A case of a 46-year-old male with ppDLE is presented.
- This patient also exhibited rare perineal involvement.
- Diagnosis was confirmed via biopsy and serological tests.
Findings:
- The patient tested positive for RNP and Sm antibodies.
- This indicates a potential autoimmune systemic component.
- Atypical DLE presentations were noted.
Implications:
- Recognizing unusual DLE manifestations is important.
- Atypical DLE may signal increased risk of systemic progression.
- Tailored management strategies are necessary for these patients.
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