Related Experiment Video
Updated: May 27, 2025

Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
Published on: December 18, 2012
A Rare Finding of Herpes Simplex Virus Esophagitis Concomitant With Duodenitis in an Immunocompetent Host
Sergio Sbeih1, Gaelle-Christie Haddad1, Nicolas Moussallem1
1Department of Internal Medicine, University of Balamand, Beirut, Lebanon.
Abstract:
Herpes simplex virus (HSV) esophagitis and duodenitis are well-known features of herpes virus reactivation in immunosuppressed patients. We discuss the case of HSV esophagitis concomitant with duodenitis in an immunocompetent individual. A 77-year-old male patient, previously healthy, was found to have on upper endoscopy several ulcers in the esophagus and second portion of the duodenum. A diagnosis of HSV esophagitis concomitant with duodenitis was made. The patient was started on intravenous acyclovir, and 48 hours after treatment, his symptoms significantly improved. He was then discharged on acyclovir per os for a total of 14 days. Endoscopy 1 month later showed complete resolution of both esophageal and duodenal ulcers. Physicians should keep the diagnosis of HSV esophagitis with duodenitis in the differentials in the setting of odynophagia, dysphagia, and epigastric pain, even in the case of an immunocompetent individual. Further research is needed to strengthen the literature on this topic.
Related Concept Videos
Immunodeficiency Diseases
There are three main causes of immunodeficiency...
Sexually Transmitted Infections
Viral Recombination
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Immune Response Against Viral Pathogens
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...

