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Related Concept Videos

Depression: Overview01:18

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Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
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Related Experiment Video

Updated: May 27, 2025

A Common Marmoset Model of Mother-Infant Intervention for Breastfeeding Disorders in the Presence of Paternal Inhibition and Maternal Neglect
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A Common Marmoset Model of Mother-Infant Intervention for Breastfeeding Disorders in the Presence of Paternal Inhibition and Maternal Neglect

Published on: September 22, 2023

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Breastfeeding interventions for preventing postpartum depression.

Mikaela Lenells1,2, Eleonora Uphoff3, David Marshall3

  • 1Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.

The Cochrane Database of Systematic Reviews
|February 18, 2025
PubMed
Summary

Breastfeeding support interventions may prevent postpartum depression and increase breastfeeding duration. However, evidence for other effects is uncertain, and more research is needed.

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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
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Area of Science:

  • Mental Health
  • Perinatal Care
  • Maternal-Infant Health

Background:

  • Postpartum depression (PPD) affects 6-13% of women in high-income countries, impacting maternal well-being and child development.
  • PPD can negatively affect breastfeeding duration and exclusivity.
  • Positive breastfeeding experiences may reduce the risk of PPD.

Purpose of the Study:

  • To assess the benefits and harms of breastfeeding support interventions on maternal postpartum depression.
  • To evaluate the impact of these interventions on depression symptoms and breastfeeding duration/exclusivity.

Main Methods:

  • Systematic review and meta-analysis of 10 randomized controlled trials (RCTs) involving 1573 participants.
  • Inclusion criteria focused on RCTs evaluating educational, psychosocial, pharmacological, alternative, or herbal breastfeeding support interventions.
  • Data extraction and risk of bias assessment were performed independently by two reviewers.

Main Results:

  • Low-certainty evidence suggests psychosocial breastfeeding interventions may prevent postpartum depression in the short term (1-3 months post-intervention).
  • Low-certainty evidence indicates psychosocial interventions may increase long-term breastfeeding duration.
  • Evidence regarding the effect of psychosocial and alternative interventions on other outcomes, including depression symptoms and exclusive breastfeeding rates, is very uncertain.

Conclusions:

  • Psychosocial breastfeeding interventions show potential for preventing short-term postpartum depression and increasing long-term breastfeeding duration.
  • The evidence base for other outcomes and for alternative interventions is limited and highly uncertain.
  • Future research should prioritize well-designed, large-scale RCTs to provide more definitive evidence on breastfeeding interventions and their impact on maternal mental health.