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Updated: May 27, 2025

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
Striving Towards Equity in Cardiovascular Genomics Research
Javier Jurado Vélez1, Nekayla Anderson2, Ivree Datcher2
1Marnix E Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Purpose Of Review:
Our review emphasizes recent advancements and persisting gaps in cardiovascular genomics, particularly highlighting how emerging studies involving underrepresented populations have uncovered new genetic variants associated with cardiovascular diseases.
Recent Findings:
Initiatives like the H3Africa project, the Million Veterans Program, and the All of Us Research Program are working to address this gap by focusing on underrepresented groups. Additionally, emerging research is centering on the interplay between genetic factors and socio-environmental determinants of health, which disproportionately impact marginalized communities. As cardiovascular genomics research grows, increasing the inclusion of underrepresented populations is essential for gaining a more comprehensive understanding of genetic variability. This will lead to more accurate and clinically meaningful strategies for preventing and treating cardiovascular diseases across all ancestral backgrounds and diverse populations.
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