[Progress in research of health economics in HIV/AIDS prevention and treatment based on CiteSpace software analysis]

Objective: An overview of the progress of health economics research in HIV/AIDS prevention and treatment based on CiteSpace analysis. Methods: With the help of visual literature analysis software CiteSpace 6.3.R1, English literature databases Web of Science, PubMed, Chinese literature databases CNKI, Wanfang Data Knowledge Service Platform, and Vip.com were searched to review the Chinese and English literature on health economics research in the field of AIDS prevention and treatment from 2010 to 2023. According to the literature clues, the main model methods in this field are supplemented. Results: The number of English publications averaged 468 per year and showed a gradual decline after reaching a peak in 2018. The number of Chinese publications averaged 50 per year and continued to decline after reaching a peak in 2014. The English literature mostly came from the CDC, HIV/AIDS medical institutions, and university medical departments in Boston, Seattle, and Washington. Most Chinese literature came from the China CDC, Shandong University, Anhui Medical University, etc. The keywords in the English literature study were antiviral treatment, South Africa, HIV detection, and pre-exposure prophylaxis (PrEP), respectively. The most frequent keywords in Chinese literature research are prostitution, mother-to-child transmission, entertainment places, and health education. Measurement methods on AIDS prevention and control service cost mainly include a top-down method, bottom-up method, activity-based costing method, etc; theoretical models are mainly HIV dynamic transmission model, Markov model optimization, and individual-based HIV comprehensive transmission model. Commonly used software tools are Spectrum, Optima HIV, MicroCOSM, EMOD-HIV, etc. Conclusions: In the field of HIV/AIDS prevention and control from 2010 to 2023, the number of English health economics research papers remained at a high level, while the number of Chinese health economics related papers declined significantly. Overseas studies have basically covered the health economics evaluation of a series of whole-chain intervention modes, such as HIV screening, pre-exposure prophylaxis (PrEP), antiviral therapy (ART) and bridging care for key populations. The domestic field needs to combine technological integration and innovation in the field of prevention and control, strengthen the health economics evaluation of innovative service models such as "Internet +" intervention, HIV self-test, PrEP, and rapid ART for key populations, deepen cross-unit and interdisciplinary cooperation, and expand methodological research.