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Updated: May 27, 2025

A Method for Measuring RNA N6-methyladenosine Modifications in Cells and Tissues
Published on: December 5, 2016
The role of N(6)-methyladenosine (m6a) modification in cancer: recent advances and future directions
Xiaozhou Xie1, Zhen Fang2, Haoyu Zhang1
1Department of General Surgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Abstract:
N(6)-methyladenosine (m6A) modification is the most abundant and prevalent internal modification in eukaryotic mRNAs. The role of m6A modification in cancer has become a hot research topic in recent years and has been widely explored. m6A modifications have been shown to regulate cancer occurrence and progression by modulating different target molecules. This paper reviews the recent research progress of m6A modifications in cancer and provides an outlook on future research directions, especially the development of molecularly targeted drugs. See also the graphical abstract(Fig. 1).
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