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Updated: May 27, 2025

Teratoma Generation in the Testis Capsule
Published on: November 7, 2011
Germ Cell Neoplasia In situ in Undescended Testis: A Myth or Reality?
Pravash Ranjan Mishra1, Suvendu Purkait2, Aditya Arvind Manekar3
1Department of Anatomy, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Background:
Untreated cryptorchid testes are in risk of intratubular germ cell neoplasia and subsequently may give rise to invasive germ cell tumors.
Materials And Methods:
Tissue samples were obtained from patients undergoing orchidectomy or orchiopexy and were subjected to routine histopathological and immunohistochemical examinations.
Results:
Forty-three patients were enrolled in this study out of which 30 samples were collected. The mean age of patients was 9.16 years. One case (6.7%) showed positivity of the germ cell neoplasia with anto placental alkaline phosphatase and Anto CD-117 positive. Other histopathological findings such as fibrocollagenous tissue and Leydig cell hyperplasia were reported.
Conclusion:
Early surgical management is of importance for a better outcome in cases of undescended testes.
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