Related Experiment Video
Updated: May 11, 2026
08:22
Permanent Cerebral Vessel Occlusion via Double Ligature and Transection
Published on: July 21, 2013
14.9K
Acute Concurrent Cardiocerebral Infarction Associated With Trousseau Syndrome: A Case Report
Aika Okubo1, Shunya Sugai2, Kyoko Morikawa3
1Cardiology, Niigata City General Hospital, Niigata, JPN.
Cureus
|February 19, 2025
Summary
This case report details a patient with Trousseau syndrome and uterine cancer who experienced acute cardiocerebral infarction. Early diagnosis and treatment, including anticoagulation, led to a favorable recovery.
Area of Science:
- Oncology
- Cardiology
- Neurology
Background:
- Trousseau syndrome, characterized by migratory thrombophlebitis, is a rare paraneoplastic syndrome associated with malignancy.
- Malignancies, particularly adenocarcinomas, are known triggers for hypercoagulable states.
Observation:
- A 66-year-old woman presented with acute aphasia and right hemiplegia due to multiple cerebral infarctions.
- Diagnostic workup revealed an asymptomatic myocardial infarction (MI) and stage IB endometrioid uterine carcinoma.
- The patient was diagnosed with Trousseau syndrome due to the co-occurrence of malignancy and multiple thrombotic events.
Findings:
- The patient experienced acute cardiocerebral infarction (CCI) secondary to Trousseau syndrome associated with stage IB uterine cancer.
- Treatment included hysterectomy, chemotherapy, and anticoagulation therapy (heparin followed by apixaban).
- The patient recovered well without recurrent thrombotic events.
Implications:
- This case highlights the critical importance of recognizing Trousseau syndrome in patients presenting with multiple cerebral infarctions.
- It underscores the necessity of screening for asymptomatic myocardial infarction in such patients, even without typical cardiac symptoms.
- Early identification and management of Trousseau syndrome can improve patient outcomes and prevent severe thromboembolic complications.
Keywords:
cardiocerebral infarctionischemic strokemyocardial infarctiontrousseau syndromeuterine cancerMore Related Videos
Related Concept Videos
01:30Acute Coronary Syndrome I: Introduction
Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
01:19Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
01:15Ischemic Stroke l: Introduction
Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
01:17Hemorrhagic Stroke l: Introduction
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
01:29Hemorrhagic Stroke ll: Pathophysiology
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
01:26Transient Ischemic Attack l: Introduction
A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...