Related Experiment Video
Updated: Jul 9, 2026

Laparoscopic Splenectomy with Pericardial Devascularization for Hypersplenism and Esophageal Variceal Hemorrhage Due to Portal Hypertension
Published on: November 15, 2024
Pleural effusions after endoscopic variceal sclerotherapy.
Pleural effusions frequently occur after endoscopic variceal sclerotherapy, affecting nearly half of procedures. These effusions are typically exudative and associated with increased chest pain and larger sclerosant volumes.
Area of Science:
- Gastroenterology
- Pulmonology
- Medical Procedures
Background:
- Endoscopic variceal sclerotherapy is a common treatment for esophageal varices.
- Complications, such as pleural effusions, can impact patient outcomes.
- Understanding the incidence and characteristics of post-sclerotherapy pleural effusions is crucial for patient management.
Purpose of the Study:
- To determine the prevalence of pleural effusions following endoscopic variceal sclerotherapy.
- To analyze the characteristics and potential contributing factors of these effusions.
- To investigate the biochemical nature of the effusions.
Main Methods:
- Retrospective review of 30 patients undergoing 65 sclerotherapy sessions.
- Radiographic identification of pleural effusions.
- Biochemical analysis of effusions via thoracentesis.
- Comparison of clinical and procedural data between patients with and without effusions.
Main Results:
- Pleural effusions occurred in 48% of sclerotherapy sessions (31 of 65).
- Effusions were right-sided, left-sided, or bilateral, with most being small (65%).
- Patients with effusions reported more chest pain and received a larger sclerosant volume (13.2 ml vs. 8.5 ml).
- Biochemical analysis indicated an exudative nature in 11 of 12 effusions.
Conclusions:
- Pleural effusions are a frequent complication of endoscopic variceal sclerotherapy.
- The effusions are predominantly exudative, likely due to mediastinal pleura inflammation.
- Increased sclerosant volume and chest pain are associated with effusion development.
Related Concept Videos
Pleural Effusion I: Introduction
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's criteria,...
Pleural Effusion II: Symptoms and Management
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
Endoscopic Studies II: Thoracocentesis
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
Esophageal Varices-I: Introduction
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
Varicose Veins II: Diagnostic Studies and Interprofessional Care

