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Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
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Related Experiment Video

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Antimicrobial Administration Practices in Hospitalized Periparturient Goats: A Multicenter Study.

Daniela Luethy1,2, Catalina Cabrera2,3, Lisette M Coll-Roman2

  • 1Clinical Studies-New Bolton Center, University of Pennsylvania, Kennett Square, Pennsylvania, USA.

Journal of Veterinary Internal Medicine
|February 19, 2025
PubMed
Summary
This summary is machine-generated.

Antimicrobial use in periparturient goats varied significantly across nine veterinary hospitals, with 77% receiving treatments. Cesarean sections were linked to increased antimicrobial prescriptions, highlighting a need for standardized stewardship practices in goat care.

Keywords:
antibiotic choicesantimicrobial stewardshipantimicrobialscaprineceftiofurpharmacology

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Area of Science:

  • Veterinary Medicine
  • Animal Health
  • Antimicrobial Stewardship

Background:

  • Understanding antimicrobial use in goats is crucial for effective antimicrobial stewardship.
  • Periparturient does represent a vulnerable population requiring careful treatment protocols.

Purpose of the Study:

  • To document antimicrobial prescriptions for periparturient does admitted to veterinary teaching hospitals.
  • To identify factors associated with general antimicrobial administration or specific use of ceftiofur.

Main Methods:

  • A multicenter, prospective, cross-sectional study involving 198 periparturient does across nine university veterinary hospitals (October 2021-June 2022).
  • Data collected via questionnaires completed by admitting clinicians.

Main Results:

  • 77% of does received antimicrobials; oxytetracycline and ceftiofur were most common.
  • Cesarean section was significantly associated with receiving antimicrobials (OR=5.89) and ceftiofur (OR=2.54).
  • Substantial hospital-level variation in ceftiofur administration was observed (p<0.001).

Conclusions:

  • Significant heterogeneity exists in antimicrobial administration practices for periparturient goats among US veterinary teaching hospitals.
  • Cesarean sections are a key factor influencing antimicrobial use in this population.
  • Further research into antimicrobial stewardship guidelines for goats is warranted.