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In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
Published on: July 24, 2020
Recent advancements in optic disc pit maculopathy management
Tadashi Yokoi1,2, Roselind L Ni1, Meera D Sivalingam1
1Will Eye Hospital Retina Service, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Purpose Of Review:
Optic disc pit maculopathy (ODPM) is a rare yet serious condition that can lead to visual impairment. While pars plana vitrectomy (PPV) remains the gold standard for ODPM that requires treatment, there is ongoing debate regarding adjunctive surgical techniques. This review explores the latest surgical advancements and innovations in the management of ODPM from the past few years.
Recent Findings:
Vitrectomy remains an effective procedure for ODPM management, achieving high success rates. Adjunctive techniques, including internal limiting membrane (ILM) peeling, gas tamponade, and juxtapapillary laser photocoagulation, have demonstrated efficacy, though their roles remain debated. Novel approaches using ILM plugging, amniotic membrane grafts, and autologous platelet concentrate offer promise, especially in refractory cases. High-level evidence remains scarce, and most recent publications are relatively small case series. Therefore, it remains unclear whether the additional techniques confer additional benefit beyond vitrectomy alone, although the novel approaches can be effective options for refractory cases. Larger comparative studies are required to provide better evidence.
Summary:
Vitrectomy with or without additional maneuvers is an effective treatment for ODPM. Emerging adjunctive surgical techniques provide new possibilities, but further research is required to assess for comparative efficacy and optimize outcomes.
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