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Updated: Jun 26, 2026
08:40
Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
Summary
Crohn
Area of Science:
- Gastroenterology and clinical immunology.
Background:
- Crohn's disease (CD) typically affects younger individuals.
- Understanding CD in elderly patients (≥60 years) is crucial for tailored management.
Purpose of the Study:
- To define the natural history of Crohn's disease in elderly patients.
- To review clinical management and long-term prognosis in this demographic.
Main Methods:
- Retrospective review of 47 patients aged 60+ at diagnosis.
- Analysis of disease patterns, clinical presentation, and outcomes.
Main Results:
- Distal colonic involvement is frequent; extensive colonic or small bowel disease is rare.
- Perforation is a significant cause of mortality, despite generally good prognosis for distal colonic disease.
- Distal ileal disease resembles younger patients but presents more acutely with lower recurrence post-surgery.
Conclusions:
- Elderly-onset Crohn's disease has distinct characteristics, notably distal colonic involvement.
- Prompt recognition and management of complications like perforation are vital for improving outcomes in older adults.
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