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Updated: May 27, 2025
Collection, Isolation, and Flow Cytometric Analysis of Human Endocervical Samples
Published on: July 6, 2014
Lobular endocervical glandular hyperplasia: Two case report and literature review
Shenglan Tang1, Xuelu Jiang2, Xue Wang2
1Department of the First School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, People's Republic of China.
Rationale:
Lobular endocervical glandular hyperplasia is a rare proliferative lesion of the endocervical glands with an unclear pathogenesis. The condition lacks specific clinical manifestations and signs and often leading to clinical underdiagnosis and misdiagnosis.
Patient Concerns:
A 27-year-old female patient presented with a history of abnormal vaginal bleeding over the previous 3 months. An ultrasound examination revealed the presence of a cystic solid structure in the posterior wall of the cervix.The second patient is a 25-year-old woman who has undergone 3 cervical cystectomies over the past 9 years due to recurrent cervical cysts. It is regrettable to report that the cyst has now recurred.
Diagnoses:
Lobular endocervical glandular hyperplasia.
Interventions:
In consideration of the fertility needs of both patients, the gynecologists conducted a comprehensive imaging evaluation and detailed preoperative discussion, and performed ultrasound-guided hysteroscopic excision of cervical lesions and transvaginal excision of cervical lesions.
Outcomes:
Following treatment, the 2 patients exhibited a complete resolution of their clinical symptoms. Subsequent follow-up examinations demonstrated that both patients were exhibiting favorable outcomes.
Lessons:
The objective of this study is to present 2 cases of lobular endocervical glandular hyperplasia in order to facilitate a greater understanding of this rare disease among gynecologists. Furthermore, this study will describe the potential use of ultrasound-guided hysteroscopic excision of cervical lesions and transvaginal hysteroscopic excision of cervical lesions as a treatment modality for lobular endocervical glandular hyperplasia patients with fertility needs.
