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Updated: Jun 23, 2026
Isolation of Murine Embryonic Hemogenic Endothelial Cells
Published on: June 17, 2016
Isolated pulmonary epithelioid hemangioendothelioma: A case report
Rong Xuan1, Zhengsen Cui2, Liuyan Zhao1
1Department of Endocrinology and Metabolism, Hangzhou Third People's Hospital, Hangzhou, Zhejiang Province, China.
Rationale:
Pulmonary epithelioid hemangioendothelioma (P-EHE), initially named "intravascular bronchoalveolar tumor," is an exceptionally rare malignant tumor with an incidence of <1 in a million. Diagnosis depends primarily on pathological and immunohistochemical findings, and currently, there is no established treatment standard.
Patient Concerns:
A 50-year-old woman had a physical examination that revealed a lung shadow, followed by a cough and sputum. A chest computed tomography (CT) scan displayed a mass shadow in the upper lobe of the left lung. 18F-Fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/CT indicated increased uptake of a clumped shadow.
Diagnosis:
The patient underwent a wedge resection of the left upper lung and pleural biopsy, confirming P-EHE.
Interventions:
Following P-EHE diagnosis, chemotherapy, targeted therapy, and immunosuppressive therapy are administered.
Outcomes:
The patient and his family gave up the treatment because it was not satisfactory. Later, we conducted a phone follow-up and learned that the patient passed away on May 18, 2023.
Lessons:
The scarcity of P-EHE complicates its diagnosis and treatment, underscoring the importance of ongoing research to enhance our understanding of this condition.
