[Use of mathematical recombination models for mapping Escherichia coli K-12 markers]

The possibility is discussed of mapping the E. coli K-12 markers on the basis of mathematical models of recombination previously developed by the authors. The analysis showed that it is advisable to use the symmetrical crossing-over model for mapping the genes close to the selective marker. The stochastic model of recombination gives good results also for genes located in the proximal part of the chromosome.