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Intestinal microbiome in gestational diabetes - review
Katarzyna Doroszewska1, Barbara Zapała2, Tomasz Stefura3
1Artvimed Medical Center, Kraków, Poland. katarzyna.doroszewska@gmail.com.
Folia Medica Cracoviensia
|February 19, 2025
Summary
Gestational diabetes, a common pregnancy complication, is linked to changes in the gut microbiome. This review examines studies on the gut microbiome
Area of Science:
- Reproductive biology
- Microbiome research
- Metabolic disease studies
Background:
- Gestational diabetes mellitus (GDM) is a prevalent pregnancy complication.
- Significant alterations in the gut microbiota occur during pregnancy.
- The intestinal microbiota plays a role in the development of GDM.
Purpose of the Study:
- To review existing literature on the gut microbiome in relation to gestational diabetes.
- To synthesize current understanding of the gut microbiota's influence on GDM development.
Main Methods:
- Systematic literature search.
- Review and synthesis of relevant studies.
- Analysis of gut microbiome data in GDM pregnancies.
Main Results:
- Studies indicate distinct gut microbiome profiles in women with GDM compared to healthy pregnancies.
- Specific bacterial taxa and their metabolic functions are associated with GDM.
- Pregnancy-induced gut microbiota changes are further modified in the presence of GDM.
Conclusions:
- The gut microbiome is a significant factor in gestational diabetes.
- Further research into the gut microbiome could lead to novel diagnostic and therapeutic strategies for GDM.
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