Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chirality in Nature02:30

Chirality in Nature

12.7K
Chirality is the most intriguing yet essential facet of nature, governing life’s biochemical processes and precision. It can be observed from a snail shell pattern in a macroscopic world to an amino acid, the minutest building block of life. Most of the snails around the world have right-coiled shells because of the intrinsic chirality in their genes. All the amino acids present in the human body exist in an enantiomerically pure state, except for glycine - the sole achiral amino acid.
12.7K
Chirality02:25

Chirality

22.9K
Chirality is a term that describes the lack of mirror symmetry in an object. In other words, chiral objects cannot be superposed on their mirror images. For example, our feet are chiral, as the mirror image of the left foot, the right foot, cannot be superposed on the left foot.
Chiral objects exhibit a sense of handedness when they interact with another chiral object. For example, our left foot can only fit in the left shoe and not in the right shoe. Achiral objects — objects that have...
22.9K
Molecules with Multiple Chiral Centers02:25

Molecules with Multiple Chiral Centers

11.2K
Molecules that possess multiple chiral centers can afford a large number of stereoisomers. For instance, while some molecules like 2-butanol have one chiral center, defined as a tetrahedral carbon atom with four different substituents attached, several molecules like butane-2,3-diol have multiple chiral centers. A simple formula to predict the number of stereoisomers possible for a molecule with n chiral centers is 2n. However, there can be a lower number where some of the stereoisomers are...
11.2K
Chirality at Nitrogen, Phosphorus, and Sulfur02:30

Chirality at Nitrogen, Phosphorus, and Sulfur

5.7K
Chirality is most prevalent in carbon-based tetrahedral compounds, but this important facet of molecular symmetry extends to sp3-hybridized nitrogen, phosphorus and sulfur centers, including trivalent molecules with lone pairs. Here, the lone pair behaves as a functional group in addition to the other three substituents to form an analogous tetrahedral center that can be chiral.
A consequence of chirality is the need for enantiomeric resolution. While this is theoretically possible for all...
5.7K
Prochirality02:05

Prochirality

3.8K
The concept of prochirality leads to the nomenclature of the individual faces of a molecule and plays a crucial role in the enantioselective reaction. It is a concept where two or more achiral molecules react to produce chiral products. A typical process is the reaction of an achiral ketone to generate a chiral alcohol. Here, the achiral reactant reacts with an achiral reducing agent, sodium borohydride, to generate an equimolar mixture of the chiral enantiomers of the product. For example, an...
3.8K
Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)01:20

Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)

945
Two NMR-active nuclei bonded to a central atom can be involved in geminal or two-bond coupling. Geminal coupling is commonly seen between diastereotopic protons in chiral molecules and unsymmetrical alkenes, among others.
The central atom need not be NMR-active because its electrons are affected by the electron polarization of the spin-active atoms. However, spin information is transmitted less effectively than in one-bond coupling, and 2J values are usually weaker than 1J values. The energy of...
945

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Structurally Encoded Mixed Proton-Electron Transport in Tetrathiafulvalene-Based Lanthanide MOFs.

Journal of the American Chemical Society·2026
Same author

Asymmetric Diphosphane Dioxides With A-π-A-π'-D Scaffolds for High-Purity Deep-Blue Luminescence.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026
Same author

Three-State Electrochiroptical Switches Derived from Chiral Stable Carbenes.

Journal of the American Chemical Society·2026
Same author

Awareness and Understanding of Post-intensive Care Syndrome (PICS) Among Internal Medicine Residents in a Community Hospital Setting.

Cureus·2026
Same author

Enantiospecific Magnetoconductance Asymmetry in a Racemic Conglomerate Driven by Surface-Assisted Symmetry Breaking.

Journal of the American Chemical Society·2026
Same author

Beyond the Solid Solution: Ordered Enantiomerically Unbalanced Packing in Surface-Confined Tetrahelicene Monolayers.

Chirality·2026
Same journal

Chlorinated VSLSs Surpass HCFCs in CFC-11-Equivalent Emissions for Ozone Layer Depletion in China.

Nature communications·2026
Same journal

Author Correction: Charge transfer in triphenylamine-tetrazine covalent organic frameworks for solar-driven hydrogen peroxide production.

Nature communications·2026
Same journal

Vegetation browning patterns under compound soil and atmospheric dryness in northern permafrost ecosystems.

Nature communications·2026
Same journal

Voltage imaging of CA1 pyramidal cells and SST+ interneurons reveals stability and plasticity mechanisms of spatial firing.

Nature communications·2026
Same journal

Radical-omics reveals the hydrogen-abstraction pathway of isoprene oxidation.

Nature communications·2026
Same journal

Toughening elastomer via sequentially activated multi-pathway energy dissipation.

Nature communications·2026
See all related articles

Related Experiment Video

Updated: May 27, 2025

A Micropatterning Assay for Measuring Cell Chirality
08:07

A Micropatterning Assay for Measuring Cell Chirality

Published on: March 11, 2022

2.3K

Single-molecule junctions map the interplay between electrons and chirality.

Anil-Kumar Singh1, Kévin Martin2, Maurizio Mastropasqua Talamo2

  • 1Department of Chemical and Biological Physics, Weizmann Institute of Science, Rehovot, Israel.

Nature Communications
|February 19, 2025
PubMed
Summary
This summary is machine-generated.

This study reveals that helicene molecules act as both magnetic-diode and spin-valve devices. This demonstrates the atomic-scale coexistence of distinct electron-chirality interactions for advanced spintronics.

More Related Videos

Single-Molecule Förster Resonance Energy Transfer Methods for Real-Time Investigation of the Holliday Junction Resolution by GEN1
11:27

Single-Molecule Förster Resonance Energy Transfer Methods for Real-Time Investigation of the Holliday Junction Resolution by GEN1

Published on: September 18, 2019

9.4K
Probing the Structure and Dynamics of Interfacial Water with Scanning Tunneling Microscopy and Spectroscopy
10:28

Probing the Structure and Dynamics of Interfacial Water with Scanning Tunneling Microscopy and Spectroscopy

Published on: May 27, 2018

8.7K

Related Experiment Videos

Last Updated: May 27, 2025

A Micropatterning Assay for Measuring Cell Chirality
08:07

A Micropatterning Assay for Measuring Cell Chirality

Published on: March 11, 2022

2.3K
Single-Molecule Förster Resonance Energy Transfer Methods for Real-Time Investigation of the Holliday Junction Resolution by GEN1
11:27

Single-Molecule Förster Resonance Energy Transfer Methods for Real-Time Investigation of the Holliday Junction Resolution by GEN1

Published on: September 18, 2019

9.4K
Probing the Structure and Dynamics of Interfacial Water with Scanning Tunneling Microscopy and Spectroscopy
10:28

Probing the Structure and Dynamics of Interfacial Water with Scanning Tunneling Microscopy and Spectroscopy

Published on: May 27, 2018

8.7K

Area of Science:

  • Condensed Matter Physics
  • Materials Science
  • Nanotechnology

Background:

  • Electron-chirality interactions significantly influence charge and spin transport in chiral conductors.
  • These interactions are crucial for developing advanced spintronic devices.
  • An atomistic understanding of these interactions has been lacking.

Purpose of the Study:

  • To investigate the behavior of helicene-based single-molecule junctions.
  • To identify and characterize distinct electron-chirality interactions at the atomic scale.
  • To explore the potential of integrating these interactions for spintronics.

Main Methods:

  • Fabrication and characterization of helicene-based single-molecule junctions.
  • Measurement of charge and spin transport properties.
  • Analysis of electron-chirality interactions under magnetic fields.

Main Results:

  • Helicene-based junctions exhibit dual functionality as magnetic-diode and spin-valve devices.
  • Magnetic-diode behavior arises from electron angular momentum interaction with magnetic fields in a chiral medium.
  • Spin-valve functionality is due to electron spin interaction with the chiral medium.

Conclusions:

  • Demonstrates the atomic-scale coexistence of distinct electron-chirality interactions.
  • Identifies unique properties of magnetic-diode and spin-valve functionalities in helicenes.
  • Highlights the potential for novel spintronic applications by integrating these functionalities.