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Updated: May 27, 2025

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification ADCI and Dose Estimation
Published on: September 4, 2017
Validation of SSDE calculation in a modern CT scanner and correlation with effective dose
Nicola Zancopè1, Francesca De Monte2, Erica Simeone1
1Department of Physics and Astronomy "Galileo Galilei", University of Padova, Padua, Italy.
Abstract:
This study aims to validate the Size Specific Dose Estimate (SSDE) provided by a modern Computed Tomography (CT) scanner and investigate its correlation with effective dose (E). SSDE is a size-specific dosimetric index addressing the limitations of the Computed Tomography Dose Index (CTDIvol). A set of 60 CT scans of anthropomorphic phantoms, including pediatric and obese models, were acquired and analyzed. SSDE values from the CT scanner were compared with those obtained through an independent Python-based calculation and Radimetrics, a dose monitor software. While the independent calculation and the one with Radimetrics were consistently in agreement, a systematic underestimation by the scanner up to 10% was seen, particularly in chest and abdominal exams. The underestimation, however, remained within the acceptable limits set by AAPM guidelines. Furthermore, a correlation between SSDE and effective dose was identified, suggesting SSDE's potential for more accurate, size-specific radiation dose and risk assessments. These findings highlight the importance of SSDE in enhancing patient-specific dose management, though further validation using patient data is needed to confirm its clinical applicability.
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