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Updated: Apr 14, 2026

Mapping Molecular Diffusion in the Plasma Membrane by Multiple-Target Tracing MTT
Published on: May 27, 2012
Random search for a partially reactive target by multiple diffusive searchers
Byeong Guk Go1, Juyeon Yi2, Yong Woon Kim1
1Korea Advanced Institute of Science and Technology, Department of Physics, Daejeon 34141, Korea.
Abstract:
We study the first-passage problem for a partially reactive target by N identical diffusive particles in a finite d-dimensional space, laying a focus on the effects of the partial reactivity when searchers are initially excluded from the target region. By solving the Fokker-Planck equation, we obtain the mean first-passage time that exhibits a power-law dependence on the number of searchers as τ_{N}∼N^{-α}, proving that the exponent α varies with dimensionality, reactivity, and the number of searchers, and specifying conditions in which crossovers between different exponents occur. We confirm the validity of our analytic results by performing Langevin dynamics simulations for various sets of system parameters.
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