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Updated: Jun 27, 2026
Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells
Published on: June 7, 2019
Uveal Melanoma in a Child: A Case Report
Shuang Zheng1, Lian-di Liu1, Dawei Wang2
1Department of Ultrasound, Renmin Hospital, Hubei University of Medicine, Shiyan, China.
Abstract:
Uveal melanoma is a rare and highly malignant tumor. Its occurrence in children is rare and challenging to differentiate from retinoblastoma. The present work reports on the unusual case of a 4-year-old male patient who presented a mass in the right eye unresponsive to 18 days of ophthalmic artery chemotherapy. Enucleation revealed a solid black mass with high melanin content. The pathological diagnosis indicated uveal melanoma in the right eyeball, infiltrating the cornea and sclera. Whole-exome sequencing found no pathogenic gene variants. Further exploration of pathogenesis and molecular genetics is needed.
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