Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Classification of Illness01:17

Classification of Illness

7.3K
The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
7.3K
Adrenal Gland Disorders01:27

Adrenal Gland Disorders

1.3K
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
1.3K
Generalized Anxiety Disorder01:30

Generalized Anxiety Disorder

44
Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry that persists for at least six months, significantly interfering with daily functioning. Unlike situational anxiety, which arises in response to specific stressors, GAD often occurs without a clear cause. Individuals may experience disproportionate worry about work, health, or relationships. For instance, a person might continuously fear poor health despite normal medical evaluations or...
44
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

797
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
797
Decreased pulse rate01:14

Decreased pulse rate

530
Bradycardia is a medical condition in which the heart rate is slower than normal. It occurs when the heart's natural pacemaker, the sinus node, generates slower electrical impulses than the standard rhythm. In adults, bradycardia is diagnosed when the pulse rate falls below 60 beats per minute, indicating a deviation from the normal heart rate range.
There are specific risk factors that can elevate the likelihood of developing bradycardia. Advanced age is a significant factor, with...
530
Disorders of the Autonomic Nervous System01:18

Disorders of the Autonomic Nervous System

519
The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
Raynaud's disease, also known as Raynaud's...
519

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Skin Prick Testing in a Portuguese Pediatric Population: A Multicenter Cross-Sectional Study of Clinical and Allergen Sensitization Profiles.

Acta medica portuguesa·2026
Same author

Regional patterns of molecular sensitization to dust mites and pollens in a Portuguese pediatric population: a multicentric study.

Allergologia et immunopathologia·2026
Same author

An Unusual Presentation of Costello Syndrome in a Boy with Precocious Puberty and Chiari I Malformation: A Case Report.

Cureus·2025
Same author

Advanced HIV Disease in Children: Clinical Practice Cases in Portugal.

The Pediatric infectious disease journal·2025
Same author

Neonatal Seizures as a First Sign of Inferior Vena Cava Thrombosis: Diagnostic and Therapeutic Challenges.

Turkish archives of pediatrics·2025
Same author

Short- to medium-term follow-up of normoponderal children and adolescents with subclinical hypothyroidism: a retrospective study of the last 15 years.

Journal of pediatric endocrinology & metabolism : JPEM·2025

Related Experiment Video

Updated: May 27, 2025

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
05:52

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Published on: November 21, 2013

14.7K

Atypical presentation of a common condition.

Mariana Oliveira Pereira1, Rita Lages Pereira1, Fábia Carvalho1

  • 1Department of Paediatrics, Hospital de Braga, Braga, Portugal.

Journal of Neonatal-Perinatal Medicine
|February 20, 2025
PubMed
Summary

Cow's milk protein allergy (CMPA) can manifest unusually, even without gut issues. Early diagnosis using clinical history and tests like IgE measurements is key for infants with atypical CMPA symptoms.

Keywords:
IgE-mediated allergycow’s milk protein allergyfood allergynewborn

More Related Videos

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis
06:19

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis

Published on: September 9, 2022

3.4K
Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome
05:12

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome

Published on: September 19, 2019

6.5K

Related Experiment Videos

Last Updated: May 27, 2025

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
05:52

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Published on: November 21, 2013

14.7K
Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis
06:19

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis

Published on: September 9, 2022

3.4K
Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome
05:12

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome

Published on: September 19, 2019

6.5K

Area of Science:

  • Pediatrics
  • Allergy Immunology

Background:

  • Cow's milk protein allergy (CMPA) exhibits diverse clinical presentations.
  • Gastrointestinal symptoms are common but not universally present in CMPA.
  • Atypical presentations can pose diagnostic challenges in infants.

Purpose of the Study:

  • To highlight the variability of CMPA manifestations.
  • To emphasize the importance of considering CMPA in infants with non-gastrointestinal symptoms.
  • To underscore the diagnostic approach for atypical CMPA cases.

Main Methods:

  • Case report of two infants with atypical CMPA.
  • Introduction of extensively hydrolyzed formula (eHF) for symptom management.
  • Diagnostic confirmation through specific IgE measurements and oral provocation testing.

Main Results:

  • Both infants presented with non-gastrointestinal symptoms (polyarthritis, rash, extremity swelling).
  • Symptoms resolved upon switching to eHF, supporting CMPA diagnosis.
  • Specific IgE and oral provocation test confirmed CMPA in one case.

Conclusions:

  • CMPA can present with a wide spectrum of symptoms beyond the gastrointestinal tract.
  • Clinical diagnosis, supported by objective tests, is crucial for managing CMPA.
  • Recognizing diverse CMPA presentations aids in timely and accurate diagnosis.