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A descriptive cross-sectional study on the cumulative frequency of pediatric procedural sedation in 0- to 3-year-old
Tingting Yi1, Zhiquan Lv1, Hongxia Luo1
1Department of Anesthesiology, the Affiliated Yongchuan Hospital of Chongqing Medical University, the Fifth Clinical College of Chongqing Medical University, Chongqing, China.
Insights
Young children (0-3 years) undergoing procedural sedation face risks from repeated exposure to anesthetic drugs. This study highlights significant cumulative sedation frequencies and general anesthetic use in this vulnerable age group.
Area of Science:
- Pediatric Anesthesiology
- Neurodevelopmental Pediatrics
- Pharmacology
Background:
- Infants and young children are susceptible to procedural sedation risks due to recurrent illnesses and poor adherence.
- Repeated or prolonged exposure to anesthetic and sedative drugs may adversely affect the developing brain.
Purpose of the Study:
- To analyze the cumulative frequency of pediatric procedural sedation.
- To examine the utilization of general anesthetic drugs in children aged 0 to 3 years.
Main Methods:
- A descriptive cross-sectional study was conducted.
- Data from 3439 children aged 0-3 years treated in a university Sedation Clinic in November 2021 were analyzed.
Main Results:
- 77.0% of children received 1-3 sedations, while 7.9% received 5-10 sedations.
- 27% of the pediatric patients received general anesthetics.
- No significant gender-based differences were observed across sedation frequency groups.
Conclusions:
- A notable proportion of young children (0-3 years) experience high cumulative frequencies of procedural sedation.
- This age group faces a significant risk of exposure to general anesthetics during procedures.
Abstract:
BackgroundRecurrent illnesses and poor adherence to medical procedures render infants and young children vulnerable to procedural sedation, while repeated or prolonged exposure to anesthetic medications and sedative drugs may potentially exert adverse effects on the developing brain.ObjectiveTo investigate the distribution of cumulative frequency and the use of general anesthetic drugs in pediatric procedural sedation for children aged 0 to 3 years.MethodsThe records of all children treated in the Sedation Clinic of the Children's Medical Center of our university in November 2021 were extracted as the sample. A descriptive cross-sectional study was performed, and the cumulative frequency of pediatric procedural sedation in 0- to 3-year-old children was investigated as the first endpoint.ResultsA total of 3439 independent children were included in this study, 2649 (77.0%), 471 (13.7%), 270 (7.9%) and 49 (1.4%) children with 1 to 3, 3 to 5, 5 to 10 and ≥10 rounds of the cumulative frequency of sedation, respectively, and 929 (27%) of those were identified general anesthetics using. There was no significant difference in the gender ratio of each cumulative frequency strata subgroup compared with that of the total sample.Conclusions: The present study concluded that some 0- to 3-year-old children are at risk of large cumulative frequency of pediatric procedural sedation and high risk of general anesthetics exposure.
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