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Revolutionizing Severe Malaria Management: The Role of CytoSorb® Hemoadsorption in Treating Malaria-Induced Liver
Rosanna Carmela De Rosa1,2, Antonio Romanelli3, Roberto Giurazza4
1Department of Anesthesia and Intensive Care, Azienda Ospedaliera Rilievo Nazionale (AORN) Ospedali dei Colli - "D. Cotugno" Hospital, Naples, ITA.
Abstract:
Malaria, caused by Plasmodium falciparum (PF), can lead to severe liver dysfunction and hyperbilirubinemia, worsening the prognosis. A 53-year-old male patient with malaria-related liver dysfunction and severe hyperbilirubinemia was treated with extracorporeal hemoadsorption (EHA) with the CytoSorb® filter (CytoSorbents, Monmouth Junction, NJ), marking a turning point in his treatment. This filter, by removing inflammatory mediators and bilirubin, significantly reduced bilirubin levels and improved the patient's clinical condition. This intervention facilitated a bridging therapy, improving symptoms and preventing organ damage during antimalarial treatment. CytoSorb® in EHA shows promise in treating malaria-induced liver dysfunction, suggesting the need for further research on its broader clinical application.
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