Potential Drug Interaction Between Liraglutide and Clonazepam: A Case Report
Ali Kheradmand1, Amir Mehrvar2, Mohammad Abbasinazari3
1Department of Psychiatry, Taleghani Hospital Clinical Research Development Unit, Medical School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abstract:
Aviophobia, that is, fear of flying, is a common type of anxiety disorder. Benzodiazepines are used in the treatment of anxiety. Liraglutide is a treatment for obesity or overweight in combination with weight-related comorbidity. We present the case of a 23-year-old woman with overweight and aviophobia, who used clonazepam as antianxious protection when flying. When taking liraglutide shortly before clonazepam the efficacy of clonazepam seemed absent as the patient experienced a panic attack at the airport. This finding suggests that liraglutide may interfere with clonazepam and reduce its effect. Further research is needed to establish this association.
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