Pilocytic astrocytoma: A rare case report
Harry Galuh Nugraha1, Elsa Yoasta1, Mirna Sobana2
1Department of Radiology, Faculty of Medicine Padjadjaran University, Dr. Hasan Sadikin Hospital Bandung, Pasteur Num. 38, Pasteur, Sukajadi, Bandung, West Java 40161, Indonesia.
Insights
Pilocytic astrocytoma (PA), a common pediatric brain tumor, can cause severe symptoms due to its size. Early diagnosis through imaging and pathology is crucial for effective management and better neurological outcomes in children.
Area of Science:
- Pediatric neuro-oncology
- Neuropathology
Background:
- Pilocytic astrocytoma (PA) is a rare, low-grade glioma primarily affecting pediatric and young adult populations.
- Despite a generally favorable prognosis, PAs can grow large, leading to significant presenting symptoms, particularly in children.
Abstract:
Pilocytic astrocytoma (PA) is a rare, low-grade glioma predominantly affecting children and young adults, with a favorable prognosis and a high survival rate. Despite its' slow growth, PA often presents with significant symptoms at diagnosis due to its tendency to reach a large size, especially in pediatric patients, where compensatory mechanisms can delay detection. This case report describes a 7-year-old girl with progressive vision loss, headache, and balance disturbance. The imaging result revealed a right cerebellar mass that was in accordance with pilocytic astrocytoma and obstructive hydrocephalus. Histopathologic analysis confirmed the diagnosis with the typical features of PA such as Rosenthal fibers and eosinophilic granular bodies. This case report highlights the critical role of radiologic and histopathologic evaluations for PA diagnosis and management; also the unique presentation and challenges in managing PA, emphasizing the importance of timely intervention to optimize neurological outcomes.
