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Lower Child Opportunity Index is associated with increased health care utilization following pediatric liver
Aaron D Bennett1, Knashawn H Morales2, Yuan-Shung V Huang3
1Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Insights
Children with lower social opportunity face more hospitalizations after liver transplantation (LT). Addressing social determinants of health can reduce acute care use in pediatric LT patients.
Area of Science:
- Pediatric Health
- Transplantation Medicine
- Health Disparities Research
Background:
- Social determinants of health (SDOH) significantly impact health outcomes, including acute care needs.
- Understanding SDOH's role in pediatric liver transplantation (LT) healthcare disparities is crucial.
- Mechanisms linking SDOH to adverse outcomes in pediatric LT patients remain unclear.
Purpose of the Study:
- To investigate the association between SDOH and healthcare utilization in children post-LT.
- To identify if SDOH influence acute care use and complication rates following pediatric LT.
Main Methods:
- Retrospective study merging data from the Organ Procurement and Transplantation Network (OPTN) and Pediatric Health Information System (PHIS) databases.
- Utilized the Child Opportunity Index (COI), a composite measure of SDOH, to stratify patients.
- Analyzed differences in hospital admission days and complication rates based on COI scores.
Main Results:
- Children with lower COI scores experienced 28% more hospital days in year 1 and 29% more in year 2 post-LT compared to those with higher COI.
- In the second year post-LT, 23% of children with lower COI were admitted with complications versus 18% with higher COI.
- Lower COI scores correlated with increased acute care utilization and complication-related admissions.
Conclusions:
- Child Opportunity Index (COI) scores effectively identify pediatric LT patients at higher risk for adverse health outcomes and increased acute care use.
- COI can serve as a valuable screening tool for clinical teams to allocate resources and mitigate acute care utilization post-LT.
- Targeting interventions based on SDOH, as measured by COI, may improve outcomes and reduce healthcare burdens in pediatric liver transplant recipients.
Abstract:
Social determinants of health are known to lead to adverse health outcomes, including high acute care utilization. The mechanisms underlying health care disparities among children who have undergone liver transplantation (LT) are poorly understood. To elucidate the relationship between social determinants of health and health care utilization among children (<18 y old at the time of LT) who have undergone LT, we performed a retrospective study merging data from the Organ Procurement and Transplantation Network (OPTN) and the Pediatric Health Information System (PHIS) database. Children with lower Child Opportunity Index (COI) scores, a composite measure of social determinants of health, were admitted for 28% more days in the first year and 29% more days over the first 2 years after LT, as compared to children with higher COI. We also observed that in the second year after LT, children with a lower COI were more often admitted with a complication of LT (23%) than those with a higher COI (18%). COI may be a useful composite screening instrument for clinical teams to target resources and limit acute care use after LT.
Related Concept Videos
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Kidney Transplant II: Surgical Procedure
Kidney Transplant III: Nursing Management

