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Related Experiment Videos

María Socorro Parra-Cabrera1, Jose Zaim Delgado-Ramírez2, Angélica Rocío Ángeles-Llerenas3

  • 1Centro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública. Cuernavaca, Morelos, Mexico.. mparra@insp.mx.

Salud Publica De Mexico
|February 20, 2025
PubMed
Summary

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Women with normal pre-pregnancy BMI who gain excess weight during pregnancy face a doubled risk of delivering macrosomic infants, a common complication in gestational diabetes. Careful weight management is crucial for healthier outcomes.

Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine
  • Endocrinology

Context:

  • Gestational diabetes mellitus (GDM) affects a significant number of pregnancies worldwide.
  • Excessive gestational weight gain (GWG) is a known risk factor for adverse pregnancy outcomes.
  • Macrosomia, or excessively large infant size, is a primary concern in GDM pregnancies.

Purpose:

  • To investigate the association between gestational weight gain in women diagnosed with gestational diabetes and the risk of macrosomia.
  • To determine if pre-pregnancy body mass index (BMI) modifies this association.

Summary:

  • A cohort study of 139 women with GDM analyzed GWG in relation to macrosomia risk.
  • Women with normal pre-pregnancy BMI who gained excessive weight had double the odds of macrosomia (OR=2.08).

Related Experiment Videos

  • Macrosomia was the most frequent complication, occurring in 12.3% of infants.

    • Impact:

    • Highlights the critical role of appropriate GWG, particularly for normal-weight GDM patients.
    • Informs clinical guidelines for managing GDM and preventing fetal overgrowth.
    • Emphasizes the need for personalized nutritional and lifestyle interventions during pregnancy.