Related Experiment Videos
Lina Sofía Palacio-Mejía1, Mariana Álvarez-Aceves2, Nils Ramírez-Knape3
1Centro de Investigación en Evaluación y Encuestas, Instituto Nacional de Salud Pública. Cuernavaca, Morelos, Mexico.. lpalacio@insp.mx.
Salud Publica De Mexico
|February 20, 2025
Summary
Chronic kidney disease (CKD) affects nearly half of the diabetic population in Jalisco, Mexico, significantly increasing premature mortality risk. Early CKD detection and intervention are crucial for improving survival outcomes in this vulnerable group.
Area of Science:
- Nephrology
- Public Health
- Epidemiology
Context:
- Diabetes mellitus is a leading cause of chronic kidney disease (CKD).
- Population-based screening for CKD in diabetic individuals is essential for understanding disease burden.
- Administrative data provides a valuable resource for epidemiological studies in large populations.
Purpose:
- To estimate survival outcomes in a diabetic population screened for CKD.
- To identify characteristics associated with premature mortality in this cohort.
- To analyze the impact of CKD on survival in Jalisco, Mexico.
Summary:
- 44% of the screened diabetic cohort had impaired renal function.
- The overall mortality rate was 14%, with 2.5% linked to CKD, and 8.7% premature deaths (8,036 Years of Life Lost).
- Survival at 8 years decreased from 93% (normal renal function) to 41% (eGFR <30 mL/min/1.73m²), with risk factors including advanced CKD, longer diabetes duration, hypertension, amputations, retinopathy, and smoking.
Impact:
- High prevalence of renal impairment highlights the urgent need for proactive CKD management in diabetic populations.
- Timely detection and protocolized interventions for CKD can significantly mitigate mortality.
- Findings underscore the importance of integrated care for diabetes and kidney disease.