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Updated: May 27, 2025

In Vivo Wireless Optogenetic Control of Skilled Motor Behavior
Published on: November 22, 2021
Acting together: Cortex and striatum specify movement kinematics
Michelle Sánchez Rivera1, Ian Duguid2
1Centre for Discovery Brain Sciences, Edinburgh Medical School: Biomedical Sciences, University of Edinburgh, Edinburgh EH8 9XD, UK.
Abstract:
In this issue of Neuron, Park et al.1 show that striatal activity is necessary for the specification of movement kinematics using a novel reach-to-pull task for mice. Through simultaneous cortical and subcortical recordings and manipulations, they demonstrate that motor cortex and striatum conjointly specify parameters necessary for shaping flexible, goal-directed actions.
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