Related Experiment Video
Updated: May 27, 2025

04:34
Surgical Treatment of an Endolymphatic Sac Tumor
Published on: May 26, 2023
569
Paraneoplastic KLHL11 encephalitis presenting with progressive tinnitus, hearing loss and ataxia
Azza Mahmoud1, Divyanshu Dubey2, Ajith Goonetilleke3
1Neurology, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE mahmoua5@clevelandclinicabudhabi.ae.
Practical Neurology
|February 20, 2025
Abstract:
Limbic encephalitis is associated with various tumours and antibodies. We describe a 33-year-old man with progressive cochleovestibular symptoms, cerebellar ataxia, myoclonus and antibodies against Kelch-like protein 11 (KLHL11). MR scan of the brain showed hippocampal T2 hyperintensities. FDG PET scan was normal. Biopsy of his enlarged left testes showed fibrosis without neoplasia. Immunotherapy so far has not helped significantly.

