Underlying factors that affect ultrasound conspicuity of breast biopsy markers: an exploratory study

  • 0Beckman Institute for Advanced Science and Technology, The Grainger College of Engineering, Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, USA.

Summary

This summary is machine-generated.

Ultrasound clip conspicuity in breast cancer management is affected by viewing angle, not off-gassing. Adjusting scanner settings may not fully recover visibility if repositioning fails.

Area Of Science

  • Medical Imaging
  • Surgical Oncology

Background

  • Neoadjuvant systemic therapy (NST) is used for node-positive breast cancer to reduce surgery.
  • Ultrasound-guided biopsy clips are standard for marking positive nodes but can become difficult to visualize after NST.
  • Poor understanding of clip conspicuity changes hinders accurate localization for subsequent procedures.

Purpose Of The Study

  • To investigate mechanisms affecting ultrasound clip conspicuity after neoadjuvant therapy.
  • To determine if ultrasound scanner settings can improve clip visibility.

Main Methods

  • Assessed the effect of viewing angle on the brightness of five commercial clips in gelatin phantoms.
  • Evaluated clip conspicuity over time ex vivo to rule out off-gassing effects.

Main Results

  • Clip brightness varied significantly with viewing angle for certain clips.
  • No evidence of clip conspicuity changes due to off-gassing was observed over time.

Conclusions

  • Viewing angle, influenced only by probe position, is a key factor in clip conspicuity.
  • Ultrasound scanner settings cannot compensate for poor visibility caused by viewing angle.
  • Other bright structures in the ultrasound field can also obscure clip location.