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QuantumNet: An enhanced diabetic retinopathy detection model using classical deep learning-quantum transfer learning
Manish Bali1, Ved Prakash Mishra1, Anuradha Yenkikar1,2
1School of Engineering, Amity University Dubai Campus, Dubai, 25314, UAE.
Methodsx
|February 21, 2025
Summary
QuantumNet, a hybrid deep learning and quantum computing model, significantly improves diabetic retinopathy (DR) detection accuracy. This advanced approach offers a more efficient and precise diagnostic tool for this diabetes-related eye condition.
Area of Science:
- Ophthalmology
- Medical Imaging
- Quantum Computing
Background:
- Diabetic Retinopathy (DR) is a diabetes-related eye condition that damages retinal blood vessels, potentially causing vision loss.
- Early and accurate DR diagnosis is crucial but challenging due to subtle and varied symptoms.
- Classical deep learning (DL) models have limitations in resource efficiency and accuracy for DR detection.
Purpose of the Study:
- To introduce QuantumNet, a novel hybrid model combining classical DL with quantum transfer learning for enhanced DR detection.
- To evaluate the performance of QuantumNet against established classical DL models.
- To demonstrate the potential of quantum computing in improving medical imaging diagnostics.
Main Methods:
- Classical DL models (CNN, ResNet50, MobileNetV2) were evaluated on the APTOS 2019 dataset.
- The best-performing classical model was integrated with a variational quantum classifier for QuantumNet.
- Quantum transfer learning was employed, with validation using statistical metrics and Google Cirq.
Main Results:
- QuantumNet achieved an accuracy of 94.11% in DR detection.
- This represents an 11.93 percentage point improvement over existing classical DL models.
- The hybrid model demonstrated high accuracy and resource efficiency.
Conclusions:
- QuantumNet offers a transformative solution for accurate and efficient diabetic retinopathy detection.
- The study highlights the significant potential of hybrid quantum-classical approaches in medical imaging.
- QuantumNet paves the way for broader applications of quantum computing in healthcare diagnostics.

