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Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance
Published on: December 28, 2017
Challenges in Diagnosing and Treating Fungal Endocarditis: A Case Report of Recurrent Candida Endocarditis in a
Ghaidaa A Almuhammadi1, Rawia A Alzughaibi1, Lamar A Amer1
1College of Medicine, Taibah University, Medinah, Saudi Arabia.
Abstract:
Fungal endocarditis (FE) is a rare yet life-threatening condition, especially in hemodialysis (HD) patients with indwelling long-term catheters. Symptoms often overlap with non-fungal infective endocarditis, making diagnosis difficult. As FE incidence increases, healthcare providers face challenges in diagnosing and managing this severe condition. Early suspicion of FE is crucial for patients with long-term catheters. We reported a 23-year-old male with end-stage renal disease (ESRD) on HD that developed FE affecting the tricuspid valve, requiring valve replacement and anti-fungal medication. Despite these interventions, he had recurrent Candida prosthetic endocarditis (CPE). Currently, he is receiving anti-fungal medication, with plans for a third surgery.
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