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Peripheral edema associated with trazodone: a report of ten cases

J Barrnett, A Frances, J Kocsis

Journal of Clinical Psychopharmacology

|June 1, 1985

Abstract:

Ten depressed patients treated with trazodone developed edema and weight gain that was promptly reversed by reduction or discontinuation of trazodone. This suggests a dose-dependent effect. None of the patients had an active medical problem that might predispose to edema formation. Summary data on all 10 cases and three case histories are presented to alert physicians to this side effect.

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