Related Experiment Video
Updated: Aug 8, 2026

06:24
Minimal Erythema Dose (MED) Testing
Published on: May 28, 2013
Erythema gyratum repens unassociated with internal malignancy
Journal of the American Academy of Dermatology
|May 1, 1985
Summary
Erythema gyratum repens, a rare skin condition, was observed in a 68-year-old man. Extensive follow-up over 39 months and autopsy confirmed no associated malignancy, despite the condition
Area of Science:
- Dermatology
- Oncology
Background:
- Erythema gyratum repens (EGR) is a rare, superficial migratory erythema.
- EGR is strongly associated with internal malignancy, often preceding its diagnosis.
Observation:
- A case of EGR in a 68-year-old male patient is reported.
- The patient underwent a 39-month evaluation period for potential malignancy.
- The patient's death was due to unrelated causes, with autopsy confirming no malignancy.
Findings:
- Despite the characteristic skin findings of EGR, no underlying malignancy was detected during the follow-up period.
- Autopsy findings also ruled out any neoplastic process.
Implications:
- This case suggests that EGR may occasionally occur without an associated malignancy.
- It highlights the importance of thorough but potentially prolonged evaluation in suspected EGR cases.
- Further research is needed to understand the specific pathobiology of EGR and its variable association with cancer.
More Related Videos
09:37Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
06:15Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Related Concept Videos
Mitogens and the Cell Cycle
Mitogens and their receptors play a crucial role in controlling the progression of the cell cycle. However, the loss of mitogenic control over cell division leads to tumor formation. Therefore, mitogens and mitogen receptors play an important role in cancer research. For instance, the epidermal growth factor (EGF) - a type of mitogen and its transmembrane receptor (EGFR), decides the fate of the cell's proliferation. When EGF binds to EGFR, a member of the ErbB family of tyrosine kinase...
Abnormal Proliferation
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
Papillary Dermis
Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Skin Cancer
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...