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Updated: May 26, 2025

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 2
Published on: April 10, 2009
Atypical Mpox Cutaneous Presentation After Full Vaccination
Celine M Schreidah1, Blair A Jenkins2,3, Megan H Trager2
1Columbia University Vagelos College of Physicians & Surgeons, New York, NY.
Abstract:
In 2022-2023 mpox outbreak led to declaration of a public health emergency. Smallpox vaccination has led to increased immunity and a decrease in clinical disease. The role of vaccination in immunosuppressed patients is not well understood. We present an atypical case of cutaneous mpox, presenting in a fully vaccinated, immunosuppressed, HIV-negative patient as an initial isolated, subcutaneous neck mass. We review the diagnostic dilemma and workup for these atypical cases.
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