Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: May 26, 2025

Author Spotlight: Minimally Invasive Relief for Occipital Neuralgia at the Nuchal Line

Author Spotlight: Minimally Invasive Relief for Occipital Neuralgia at the Nuchal Line

Published on: September 13, 2024

Predecompression and postdecompression cognitive and affective changes in Chiari malformation type I.

Luke C Henry¹, Michael M McDowell¹, Tina L Stephenson²

¹Departments of1Neurological Surgery.

Journal of Neurosurgery

|February 21, 2025

Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Perception and Performance of a Novel Suction-Integrated Malleable Retractor.

Operative neurosurgery (Hagerstown, Md.)·2026

Same author

Spinal and Paraspinal Injuries from Weightlifting in Minors.

World neurosurgery·2026

Same author

Investigating Physiology-Behavior Associations for Youth During Parent-Child Conflict Discussions.

Developmental psychobiology·2026

Same author

Graded extent of hippocampal resection is related to neuropsychological outcomes in temporal lobe epilepsy surgery.

Epilepsia·2026

Same author

Risk Factors for Delayed Leptomeningeal Dissemination in Choroid Plexus Papillomas: A Systematic Review and Illustrative Case.

Current oncology (Toronto, Ont.)·2026

Same author

Safety of endovascular shunting for normal pressure hydrocephalus from a prospective, multicenter, single-arm study.

Journal of neurointerventional surgery·2026

Same journal

Extent of resection as an independent predictor of survival for patients with glioblastoma as defined by the new WHO 2021 classification.

Journal of neurosurgery·2026

Same journal

Surgical treatment of schwannomas around the tarsal tunnel: a case series of 40 patients and systematic review of the literature.

Journal of neurosurgery·2026

Same journal

Direct targeting for focused ultrasound thalamotomy in the treatment of movement disorders.

Journal of neurosurgery·2026

Same journal

Development and internal validation of the Meningioma Functional Outcome Risk and Counseling Estimator 6 score, a point-based prognostic tool for predicting 6-week functional independence after intracranial meningioma resection.

Journal of neurosurgery·2026

Same journal

Connectional anatomy of the cerebellum: dentate nucleus and cerebellar peduncles from a surgical perspective.

Journal of neurosurgery·2026

Same journal

Press releases in neurosurgery: is scientific accuracy compromised in public reporting of neurosurgery research?

Journal of neurosurgery·2026

See all related articles

This summary is machine-generated.

Chiari malformation type I (CM-I) patients show cognitive and psychiatric issues. Surgery improved these symptoms, suggesting the cerebellum

Area of Science:

Neuroscience
Neurosurgery
Psychiatry

Background:

The cerebellum's role in cognition and psychiatric conditions is understudied, especially in Chiari malformation type I (CM-I).
Cognitive and psychiatric symptoms in CM-I patients are often unrecognized and their link to cerebellar function is unclear.

Purpose of the Study:

To assess pre- and postoperative cognitive and psychiatric function in CM-I patients.
To investigate if cerebellar-targeted interventions can improve cognitive and psychiatric symptoms in CM-I.

Main Methods:

Prospective study of 54 CM-I patients with cognitive or psychiatric dysfunction.
Standardized neuropsychological and psychiatric assessments pre- and 6 months post-surgery.
Exclusion of patients with severe preoperative cognitive deficits ( >3.5 SDs).

Keywords:

Chiari cerebellum cognition decompression surgery neuropsychology psychiatric

More Related Videos

Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression

Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression

Published on: May 7, 2019

Author Spotlight: Development and Application of a Novel Suture Technique for Annular Fibrosus Repair in Percutaneous Transforaminal Endoscopic Discectomy

Author Spotlight: Development and Application of a Novel Suture Technique for Annular Fibrosus Repair in Percutaneous Transforaminal Endoscopic Discectomy

Published on: January 26, 2024

Related Experiment Videos

Last Updated: May 26, 2025

Author Spotlight: Minimally Invasive Relief for Occipital Neuralgia at the Nuchal Line

Author Spotlight: Minimally Invasive Relief for Occipital Neuralgia at the Nuchal Line

Published on: September 13, 2024

Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression

Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression

Published on: May 7, 2019

Author Spotlight: Development and Application of a Novel Suture Technique for Annular Fibrosus Repair in Percutaneous Transforaminal Endoscopic Discectomy

Author Spotlight: Development and Application of a Novel Suture Technique for Annular Fibrosus Repair in Percutaneous Transforaminal Endoscopic Discectomy

Published on: January 26, 2024

Main Results:

Preoperatively, CM-I patients exhibited deficits in executive function, visuospatial memory, and increased psychiatric symptoms.
Post-surgery, 89% of patients demonstrated clinically significant cognitive and/or psychiatric improvements.

Conclusions:

CM-I patients present with significant cognitive and psychiatric impairments.
Posterior fossa decompression surgery led to symptom improvement, indicating treatable dysfunction in some CM-I patients.
This study underscores the cerebellum's potential involvement in cognitive and psychiatric disorders.