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Updated: May 26, 2025

Quantifying the Binding Interactions Between CuII and Peptide Residues in the Presence and Absence of Chromophores
Published on: April 5, 2022
A new dithieno[2,3-b]pyridine-fused BODIPY fluorescent probe for specific Cu2+ recognition
Huimin Zhou1, Shulin Gao1, Zhehui Weng1
1Yunnan Key Laboratory of Metal-Organic Molecular Materials and Device, School of Chemistry and Chemical Engineering, Kunming University, Kunming 650214, China.
Abstract:
In this study, we developed a novel fluorescent probe (BPS) based on dithieno[2,3-b]pyridine-fused BODIPY, which demonstrated excellent photophysical properties. BPS enables the sensitive and specific detection of Cu2+, with a detection limit of 17 μM, allowing for trace detection. Additionally, BPS exhibits strong anti-interference ability, maintaining selectivity for Cu2+ even in the presence of other ions. It produces a clearly visible color change under both natural light and 365 nm UV light. Importantly, BPS is particularly effective for detecting copper ions in real water samples. With its high sensitivity and specific recognition of copper ions, BPS provides an effective analytical tool for environmental monitoring and bioanalysis, making it highly promising for applications in analytical chemistry and environmental safety.

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