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Published on: March 7, 2020
Association between objective physical activity and frailty transition in community-dwelling prefrail Japanese older
Yu-Shan Lee1, Yukiko Nishita2, Chikako Tange2
1Center for Geriatrics & Gerontology, Taichung Veterans General Hospital, Taichung, Taiwan; Department of Epidemiology of Aging, Research Institute, National Center for Geriatrics and Gerontology, Aichi, Japan.
Background:
Frailty transition is common, and increased physical activity can prevent it. An objective assessment of physical activity could eliminate bias and provide more precise information on the association between frailty transitions and physical activity.
Objectives:
This study aimed to examine the association between objective physical activity and frailty transition in community-dwelling prefrail Japanese older adults.
Design:
This is a retrospective cohort study based on the National Institute for Longevity Science-Longitudinal Study of Aging data.
Participants:
A total of 387 community-dwelling older adults with prefrailty were enrolled (mean age 72.0 years).
Measurements:
Frailty was assessed using modified components of the Cardiovascular Health Study criteria, and frailty statuses were reassessed two years later. The frailty transitions were categorized into three groups: deterioration, persistence, and reversal. Participants wore a uniaxial accelerometer to assess the physical activities. Differences in baseline characteristics according to frailty transitions were assessed. To compare the baseline objective physical activities based on frailty transition, a general linear model and a logistic regression model were used.
Results:
Among the 387 participants, 40 (10.3%) deteriorated to frailty, 97 (25.0%) reversed to robust, and the majority (n = 250, 64.6%) remained prefrail after a 2-year follow-up. Using the general linear model, after adjusting for other factors, total energy expenditure (TEE) in the reversal group was significantly higher than that in the deterioration and persistence groups. No differences in TEE were observed between the persistence and deterioration groups. No significant differences existed in the numbers of daily steps, exercise energy expenditure (EEE) and physical activity with different intensity among these three groups. The logistic model also showed a significant association between TEE and the reversal of frailty.
Conclusion:
Frailty transitions were common in the Japanese prefrail population. This study showed that a higher TEE was positively associated with frailty reversal in prefrail older adults. Promoting proactive programs for older adults to increase physical activity could help them stay healthy and prevent frailty deterioration.
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