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Related Experiment Videos

Human sympathetic electrical activity recorded with skin surface electrodes.

V I Skok, I N Remizov, L V Melnichenko

    Journal of the Autonomic Nervous System
    |February 1, 1985
    PubMed
    Summary

    Researchers detected subtle electrical signals in humans, similar to those in rabbits, suggesting a sympathetic nervous system origin. This finding may improve understanding of autonomic nervous system activity.

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    Area of Science:

    • Neuroscience
    • Physiology
    • Biomedical Engineering

    Background:

    • Spontaneous electrical activity linked to cardiac rhythm has been previously recorded.
    • Previous methods utilized electrodes on the human arm or rabbit hindlimb.

    Purpose of the Study:

    • To investigate and characterize spontaneous electrical activity in humans.
    • To explore the sympathetic nervous system's role in this activity.
    • To improve the signal-to-noise ratio of recorded bioelectrical signals.

    Main Methods:

    • Electrodes were placed on the human arm and rabbit hindlimb for recording.
    • Electrocardiogram (ECG) synchronization and record averaging were used to enhance signal quality.
    • Direct electrical stimulation of sympathetic nerves in rabbits was performed.

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  • Conduction velocity and time course of electrical activity were analyzed.

    • Main Results:

    • A slow, negative, sinusoid-like wave with a mean peak amplitude of 0.08 +/- 0.03 microV was recorded in humans.
    • The recorded human activity exhibited similar time course and conduction velocity to sympathetic nerve activity in rabbits.
    • Electrical stimulation of sympathetic nerves in rabbits yielded recordable skin surface responses.

    Conclusions:

    • The findings suggest a sympathetic nervous system origin for the recorded human electrical activity.
    • The study demonstrates a non-invasive method for potentially assessing sympathetic nerve function in humans.
    • Improved signal processing techniques enhance the detection of low-amplitude bioelectrical signals.