Related Experiment Video
Updated: May 26, 2025
04:58
Method of Studying Palatal Fusion using Static Organ Culture
Published on: September 19, 2015
8.7K
Differences in Tooth Development in Patients With Unilateral Cleft Lip and Palate.
Marie Schwarting1, Heinrich Wehrbein1, Irene Schmidtmann2
1Department of Orthodontics, University Medical Center at the Johannes Gutenberg-University, Mainz, Germany.
Clinical and Experimental Dental Research
|February 22, 2025
Summary
Patients with unilateral clefts exhibit delayed tooth development and dental age, especially on the affected side. This finding suggests a need for adjusted orthodontic treatment timing to protect developing tooth roots.
Area of Science:
- Dentistry
- Orthodontics
- Pediatric Dentistry
Background:
- Unilateral cleft lip and palate (UCLP) and unilateral cleft lip and alveolus (UCLA) are common congenital conditions affecting facial development.
- Tooth development is a complex process that can be influenced by various genetic and environmental factors.
Purpose of the Study:
- To investigate and compare tooth development and dental age in patients with UCLP and UCLA compared to non-cleft controls.
- To identify specific patterns of tooth development delay in relation to the cleft side and dental arch.
Main Methods:
- A retrospective case-control study analyzed 180 panoramic radiographs from non-syndromic patients with UCLP (160) and UCLA (20).
- Patients were matched to a control group based on age, gender, and ethnicity.
- Radiographs were assessed for dental age and tooth development, with specific attention to mineralization differences.
Main Results:
- Patients with unilateral clefts demonstrated a significantly lower dental age compared to controls (mean difference of 0.69 years).
- Tooth development was notably slower on the cleft side and in maxillary teeth compared to mandibular teeth.
- Significant mineralization delays were observed in UCLP patients for lateral incisors, central incisors, and canines.
Conclusions:
- Unilateral clefts are associated with delayed tooth development and dental age, particularly within the affected quadrant.
- Clinical management should consider a delayed initiation of orthodontic tooth movement to prevent potential damage to slower-developing tooth roots.
Related Concept Videos
01:15Teeth
288
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
288
01:26Assessment of the Mouth
123
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
123