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Updated: May 26, 2025

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells
Published on: June 7, 2019
Congenital Melanocytic Nevi
Shelby Nathan1, John Smetona2, Sanjay Naran3
1Division of Plastic and Reconstructive Surgery, University of Chicago, Chicago, IL, USA.
Abstract:
Congenital melanocytic nevi are benign neoplasms, which present early in life at various anatomic locations with a variety of clinical presentations. When evaluating large or giant nevi, it's important to use a multidisciplinary team and rule out comorbid conditions, such as neurocutaneous melanosis. Surgical interventions include direct excision, serial excision, and tissue expansion. For more complex lesions, tissue expansion is a versatile and effective option for many areas of the body. Most large or giant lesions require serial excision and long-term follow-up.
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