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Updated: Jul 13, 2026
A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells
Published on: October 15, 2013
Single iron catalyst with bi-atomic matching site to construct electrochemical chip for on-site inspection of
Zhuanzhuan Shi1, Liang Liu1, Xiaoshuai Wu1
1Institute of Materials Science and Devices, School of Materials Science and Engineering, Suzhou University of Science and Technology, Suzhou, 215011, China.
Abstract:
Chloramphenicol (CAP) as an amide-alcohol antibiotic is extensively used in aquaculture industries and can accumulate in the human body through the food chain and water sources, leading to various diseases. On-site inspection of CAP remains a challenge due to the lack of portable and sensitive sensing platforms. Herein, a bi-atomic matching catalyst that comprises atomic Fe uniformly distributed on an N-doped graphene matrix (A-Fe-NG) is synthesized. An electrochemical sensor based on A-Fe-NG is constructed for CAP, demonstrating a high sensitivity of 164.2 μA μM-1 cm-2 and a fast response time of 1.2 s, among the best of Fe-based electrochemical CAP sensors. The high performance should be attributed to the high active site density of A-Fe-NG as well as the bi-atomic matching-catalysis mechanism. A portable electrochemical chip based on A-Fe-NG is also built, delivering accurate monitoring of CAP in river water for practical on-site inspection.
