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Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
87
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
295
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

32
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
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Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
378
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

158
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
158
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

114
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Related Experiment Video

Updated: May 26, 2025

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
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A practical guide to dilating inflammatory bowel disease strictures.

Natasha K Klemm1, Joseph D Feuerstein1

  • 1Division of Gastroenterology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

Expert Review of Gastroenterology & Hepatology
|February 23, 2025
PubMed
Summary

Managing stricturing Crohn's disease requires differentiating inflammatory from fibrotic strictures. Current treatments, including endoscopic balloon dilation (EBD), face high recurrence rates, necessitating further research into advanced endoscopic techniques.

Keywords:
Crohn’s diseaseStrictureinflammatory bowel diseasesurgerytreatmentulcerative colitis

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Area of Science:

  • Gastroenterology and Hepatology
  • Inflammatory Bowel Disease (IBD) Research

Background:

  • Stricturing Crohn's disease is a prevalent phenotype requiring careful management to alleviate symptoms and prevent complications.
  • Effective management is hindered by diagnostic limitations, stricture composition variability, and high recurrence rates.

Purpose of the Study:

  • To review the latest research on the detection, diagnosis, and management of inflammatory bowel disease (IBD)-related strictures.
  • To highlight current endoscopic techniques and identify future research directions in intestinal stricture treatment.

Main Methods:

  • A comprehensive literature search was conducted using the PubMed (MEDLINE database).
  • The search focused on recent advancements in the management of IBD-related intestinal strictures.

Main Results:

  • Distinguishing between inflammatory and fibrotic strictures is crucial for guiding treatment strategies.
  • While endoscopic balloon dilation (EBD) is increasingly used, high stricture recurrence rates persist, often requiring repeat interventions.

Conclusions:

  • The management of intestinal strictures in Crohn's disease presents significant challenges.
  • Future advancements are anticipated in imaging, pharmacotherapy, and interventional endoscopy for improved patient outcomes.