Related Experiment Video
Updated: May 26, 2025

09:37
Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
2.2K
Minimally invasive modalities for keratinocyte carcinomas -Part II: Treatment
Nathan Gasek1, Albert E Zhou1, Christian Gronbeck1
1Department of Dermatology, University of Connecticut School of Medicine, Farmington, Connecticut.
Journal of the American Academy of Dermatology
|February 23, 2025
Summary
Non-surgical treatments for keratinocyte carcinoma offer new options for patients avoiding surgery. This review guides providers in selecting optimal therapies for those with surgical contraindications.
Area of Science:
- Dermatology
- Oncology
Background:
- Keratinocyte carcinoma treatment has evolved beyond surgery.
- Many patients are poor surgical candidates or prefer non-surgical options.
Purpose of the Study:
- To review established and emerging non-surgical therapies for keratinocyte carcinoma.
- To guide clinicians in managing patients with surgical contraindications.
Main Methods:
- Literature review of pharmacologic, photodynamic, laser, radiation, and minimally-invasive treatments.
- Focus on evidence-based treatment and preventive strategies.
Main Results:
- A broad range of non-surgical treatment modalities are available.
- Established and emerging therapies offer alternatives to surgery for specific patient groups.
Conclusions:
- Non-surgical options are expanding for keratinocyte carcinoma management.
- Evidence-based selection of these therapies is crucial for patients with surgical contraindications.
Related Concept Videos
Skin Cancer
3.0K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
3.0K
Tumor Immunotherapy
463
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
463
Targeted Cancer Therapies
7.4K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.4K

