The efficacy and safety between efgartigimod and intravenous immunoglobulin in elderly generalized myasthenia gravis
Chaoyue Zhang1, Xiang Li1, Yufei Deng1
1The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Abstract:
The study examines efgartigimod and intravenous immunoglobulin (IVIg) in elderly patients with generalized myasthenia gravis (GMG), focusing on changes in Myasthenia Gravis Activities of Daily Living (MG-ADL) scores, pyridostigmine dosage, and minimal symptom expression (MSE) over an 8-week period. Among 74 enrolled patients, efgartigimod showed greater reduction in MG-ADL scores compared to IVIg at weeks 4 and 8, with no serious adverse events, suggesting its superior efficacy and safety in elderly Chinese patients with acetylcholine receptor antibody-positive (AChR-Ab(+)) GMG.
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