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Validation of the Toronto Upper Gastrointestinal Cleaning Score in children
Łukasz Dembiński1, Lorenzo Norsa2, Sian Copley3
1Department of Pediatric Gastroenterology and Nutrition, Medical University of Warsaw, Warsaw, Poland.
Insights
The Toronto Upper Gastrointestinal Cleaning Score (TUGCS) is a reliable tool for assessing pediatric gastroscopy quality. This validated method ensures consistent upper GI mucosal visualization in children.
Area of Science:
- Pediatric Gastroenterology
- Endoscopic Quality Assessment
- Gastrointestinal Imaging
Background:
- Gastroscopy is crucial for examining the upper GI tract in children.
- A validated method for assessing pediatric gastroscopy quality is currently lacking.
- Standardized endoscopic scales enhance study quality and inter-center consistency.
Purpose of the Study:
- To validate the Toronto Upper Gastrointestinal Cleaning Score (TUGCS) for pediatric gastroscopy.
- To assess the reliability and consistency of the TUGCS in a pediatric population.
Main Methods:
- A multicenter, prospective, single-masked study involving 10 European centers.
- Seventeen endoscopists assessed prerecorded pediatric gastroscopies using the TUGCS.
- Statistical analysis included inter-rater, intra-rater correlations, and Cronbach's alpha for internal consistency.
Main Results:
- The TUGCS showed high within-rater consistency (0.64) and excellent test-retest reliability (0.97).
- High internal consistency was confirmed (Cronbach's α = 0.95).
- No significant differences in TUGCS assessment were noted based on endoscopist experience, specialization, age, or gender.
Conclusions:
- The TUGCS is a reliable and validated tool for evaluating upper GI mucosal visualization quality in pediatric patients.
- The score is easy to learn and useful for clinical trials and standardization.
Objectives:
Gastroscopy is used to examine the upper gastrointestinal (GI) tract, but no validated method yet exists to assess the quality of mucosal visualization in children. Utilizing validated endoscopic scales can enhance study quality and standardization across centers. This study aimed to validate the existing Toronto Upper Gastrointestinal Cleaning Score (TUGCS) in pediatric patients.
Methods:
This was a multicenter, prospective, single-masked study conducted in 10 European pediatric gastroenterology centers. Endoscopists with varying degrees of experience assessed the quality of mucosal visualization in prerecorded gastroscopies using the TUGCS. Each endoscopist assessed the studies two times in random order, with an interval of at least 2 weeks. The correlations of individual and total scores were statistically compared between themselves, between assessors, and between assessment attempts. Internal consistency was also checked with Cronbach's α.
Results:
Seventeen endoscopists participated in the study. The TUGCS demonstrated high consistency within raters, with a score of 0.64 (95% confidence interval [CI]: 0.34-0.84), and an excellent test-retest reliability of 0.97 (95% CI: 0.94-0.99). The scale also showed high internal consistency, with a Cronbach's α of 0.95. The correlation between different items ranged from 0.60 to 0.77, and the correlation between individual items and the total score ranged from 0.66 to 0.88. No significant differences in the assessment were found based on the raters' experience performing endoscopy, specialization, age, or gender. The endoscopists found TUGCS easy to learn and potentially useful, especially in clinical trials.
Conclusions:
The TUGCS was demonstrated as a reliable and validated method for assessing the visualization quality of the upper GI mucosa in pediatric patients.
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