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Infection Reducing Strategies in Sacroneuromodulation: A Systematic Review
Laurel Carbone1, Rodger Rothenberger1, Hannah E Houston2
1Division of Urogynecology and Reconstructive Pelvic Surgery, University of Louisville, Louisville, Kentucky, USA.
Neurourology and Urodynamics
|February 23, 2025
Summary
Infection-reducing strategies for sacroneuromodulation (SNM) showed varied effectiveness, with no clear benefit from specific interventions like skin prep or antibiotics. Surgeons should select antibiotics based on local resistance and patient factors due to low-quality evidence.
Area of Science:
- Urology
- Neurosurgery
- Infectious Disease
Background:
- Sacroneuromodulation (SNM) is used for various lower urinary tract symptoms.
- Postoperative infections are a significant complication following SNM procedures.
- Evidence-based guidelines for infection prevention in SNM are limited.
Conclusions:
- Significant heterogeneity exists in reported infection-reducing interventions for SNM.
- Current evidence does not support specific infection-reducing strategies over others.
- Surgeons are advised to choose antibiotics based on local antibiotic resistance patterns and patient colonization until higher-quality evidence emerges.

